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Monday, November 14, 2011

Is sexual orientation depends on the serotonin?

This conclusion is part of a study that 'played' with serotonin in male mice. The mice were deprived of this neurotransmitter and found to completely lose their predilection for females. Still as any mouse mating, but males and females alike. Serotonin is a key neurotransmitter in depression and its treatment, and now it is confirmed that also affects the sexual behavior of humans. Without serotonin mice showed a behavioral change quite specific, not attracting females. And not due to a general abnormality of smell or pheromone detection, since these processes seem unaffected in mice without serotonin. In addition it was shown that these mice was sufficient to inject a compound that restores the synthesis of serotonin to regain their orientation in a little over half an hour.

Previous studies have investigated the effects on human sexual behavior on Prozac (fluoxetine), an antidepressant from the family of serotonin, showed that it is able to inhibit compulsive sexual behavior, but only gay men, not heterosexuals. This data is far from demonstrating that serotonin is involved in sexual orientation in humans, but it does point to certain effects dependent on the individual's sexual orientation.

The nature of homosexuality and has been described in mammalian species ranging from Hereford bulls to rhesus macaques, to the sheep. There is strong evidence that homosexuality has a genetic basis in humans. The twins, who share all their genes, they agree on their sexual orientation in 50% of cases, while fraternal twins share only half their genes, are consistent only in 22% of cases. Gays in the same family tend to share the same genetic variants in specific areas of chromosomes X, 7, 8 and 10.

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